# Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021.

**Organizacion:** St-Gallen
**Autores:** Burstein HJ, Curigliano G, Thurlimann B et al.
**Revista:** Ann Oncol (2021)
**PMID:** 34242744 | **PMCID:** PMC9906308
**DOI:** [10.1016/j.annonc.2021.06.023](https://doi.org/10.1016/j.annonc.2021.06.023)
**Fuente:** PubMed Central (open access)

## Relevancia
Conferencia internacional de consenso bianual; punto de referencia mundial para la toma de decisiones en cancer de mama temprano. El panel multidisciplinar vota sobre escenarios clinicos clave, incluyendo des-escalada quirurgica axilar post-NAC en pacientes cN+ que convierten a ypN0.

## Recomendaciones clave (resumen)
- Acepta BSGC post-NAC en pacientes cN+ que convierten a cN0 si se cumplen estandares de calidad (>=3 ganglios, doble trazador, marcaje del ganglio biopsiado).
- Tendencia consistente a des-escalada quirurgica axilar en respondedoras.
- Recomienda evaluacion clinica/ecografica axilar post-NAC antes de la cirugia.
- TAD (Targeted Axillary Dissection) reconocida como tecnica aceptable para reducir tasa de falsos negativos.

## Abstract
The 17th St Gallen International Breast Cancer Consensus Conference in 2021 was held virtually, owing to the global COVID-19 pandemic. More than 3300 participants took part in this important bi-annual critical review of the state of the art in the multidisciplinary care of early-stage breast cancer. Seventy-four expert panelists discussed and commented on the previously elaborated consensus questions, as well as many key questions on early breast cancer diagnosis and treatment asked by the audience. The theme of this year conference was Customizing local and systemic therapies. A well-organized program of pre-recorded symposia, live panel discussions and real-time panel voting results drew a worldwide audience of thousands, reflecting the far-reaching impact of breast cancer on every continent.

## Acceso
Disponible en PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC9906308/

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*Datos de PubMed. Citar: doi 10.1016/j.annonc.2021.06.023*
