# Is less more? Revisiting elective nodal irradiation in head and neck cancer.

**Tumor:** Cabeza y cuello
**Autores:** Haderlein M
**Revista:** Strahlenther Onkol (2025)
**PMID:** 40705060 | **PMCID:** —
**DOI:** [10.1007/s00066-025-02437-5](https://doi.org/10.1007/s00066-025-02437-5)
**Fuente:** PubMed (abstract only)

## Relevancia
Tumores de cabeza y cuello (escamoso oro/hipo/laringe/sinonasal) tras quimioterapia de inducción: respuesta ganglionar cervical, manejo del cuello residual y desescalamiento de la radioterapia ganglionar electiva. Paralelismo con mama: la respuesta locorregional a inducción permite estratificar tratamientos posteriores y modificar el manejo quirúrgico/RT del cuello.

## Abstract
Radiotherapy is an important pillar of treatment for HNSCC. Various approaches to deintensifying elective nodal irradiation (ENI) have been investigated, ranging from dose reduction, volume reduction, to complete omission of ENI, with some studies using response-adjusted dose/volume reduction after induction chemotherapy. All phase II trials indicate that the recurrence rate outside the radiation field is low (up to 4%). Reducing or even omitting ENI in HNSCC seems to be a promising approach to de-escalation, but phase III trials are still pending.

## Acceso
Vía [DOI](https://doi.org/10.1007/s00066-025-02437-5) o suscripción institucional.

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*Datos de PubMed. Citar: doi 10.1007/s00066-025-02437-5*
