# Treatment of Patients with Early Breast Cancer: 19th St. Gallen International Breast Cancer Consensus Discussed against the Background of German Treatment Recommendations.

**Organizacion:** St-Gallen
**Autores:** Untch M, Banys-Paluchowski M, Brucker SY et al.
**Revista:** Geburtshilfe Frauenheilkd (2025)
**PMID:** 40599897 | **PMCID:** PMC12208719
**DOI:** [10.1055/a-2612-3790](https://doi.org/10.1055/a-2612-3790)
**Fuente:** PubMed Central (open access)

## Relevancia
Conferencia internacional de consenso bianual; punto de referencia mundial para la toma de decisiones en cancer de mama temprano. El panel multidisciplinar vota sobre escenarios clinicos clave, incluyendo des-escalada quirurgica axilar post-NAC en pacientes cN+ que convierten a ypN0.

## Recomendaciones clave (resumen)
- Acepta BSGC post-NAC en pacientes cN+ que convierten a cN0 si se cumplen estandares de calidad (>=3 ganglios, doble trazador, marcaje del ganglio biopsiado).
- Tendencia consistente a des-escalada quirurgica axilar en respondedoras.
- Recomienda evaluacion clinica/ecografica axilar post-NAC antes de la cirugia.
- TAD (Targeted Axillary Dissection) reconocida como tecnica aceptable para reducir tasa de falsos negativos.

## Abstract
This year's 19th St. Gallen (SG) consensus conference on the treatment of patients with early breast cancer (SGBCC: St. Gallen Breast Cancer Conference) is based on numerous patient examples, each with different variables, to reflect the increasingly personalized treatment decision for early breast cancer. More than ever, not only breast cancer subtype, performance status, age and life expectancy are considered as individual factors, but various molecular and genetic variables are also part of the treatment decision. In this manuscript, the SGBCC voting results are discussed by a German group of breast cancer specialists in the context of the recently (2025) updated treatment recommendations of the Commission of the Gynecological Oncology Working Group (AGO Mamma). The German treatment recommendations are based on current evidence. As the international panel of the SGBCC consists of experts from different countries and disciplines, the votes represent an international cross-section of opinions. Therefore, it is useful to discuss the voting results with respect to current German treatment guidelines.

## Acceso
Disponible en PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12208719/

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*Datos de PubMed. Citar: doi 10.1055/a-2612-3790*
