# Feasibility of Axillary Lymph Node Localization and Excision Using Radar Reflector Localization.

**Autores:** Sun J, Henry DA, Carr MJ et al.
**Revista:** Clin Breast Cancer (2020)
**PMID:** 32893094 | **PMCID:** —
**DOI:** [10.1016/j.clbc.2020.08.001](https://doi.org/10.1016/j.clbc.2020.08.001)
**Fuente:** PubMed (abstract only — full text vía DOI)

## Relevancia
Serie institucional/registro que aporta cifras de tasas de ypN0, falsos negativos de SLNB/TAD y patrones de manejo axilar tras NAC en cáncer de mama cN+.

## Abstract
Neoadjuvant chemotherapy (NAC) is commonly used for patients with clinically detected nodal metastases. Sentinel lymph node biopsy (SLNB) after NAC is feasible. Excision of biopsy-proven positive lymph nodes in addition to SLNB, termed targeted axillary dissection (TAD), decreases the false-negative rate of SLNB alone. Positive nodes can be marked with radar reflector-localization (RRL) clips. We report our institutional experience with RRL-guided TAD and demonstrate its safety and feasibility.

We performed an institutional review board-approved retrospective review of consecutive clinically node-positive female patients with breast cancer treated with NAC and RRL-guided TAD between January 2017 and September 2019. Clinicopathologic and treatment data were collected; descriptive statistics are reported.

Forty-five patients were analyzed; the median age was 55 years (range, 20-72 years), and the median body mass index was 27.2 kg/m(range, 16.5-40.4 kg/m). All patients received NAC, primary breast surgery, and TAD. All clinically detected nodal metastases were confirmed with percutaneous biopsy and marked with a biopsy clip. RRL clips were implanted a median of 8 days (range, 1-167 days) prior to surgery; all were retrieved without complications. The RRL node was identified as the sentinel lymph node in 36 (80%) patients. Twenty-five patients had positive nodes, of which 24 were identified by RRL node excision, and 1 (4%) patient had a positive node identified by SLNB but not RRL. Over a median follow-up time of 29.6 months, 5 patients recurred (1 local, 4 distant).

RRL-guided TAD after NAC is safe and feasible. This technique allows for adequate assessment of the nodal basin and helps confirm excision of the previously biopsied positive axillary node.

## Acceso
Vía [DOI](https://doi.org/10.1016/j.clbc.2020.08.001) o suscripción institucional.

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*Datos de PubMed. Citar: doi 10.1016/j.clbc.2020.08.001*
