# A Nomogram to Predict Nodal Response after Induction Chemotherapy for Hypopharyngeal Carcinoma.

**Tumor:** Cabeza y cuello
**Autores:** Li F
**Revista:** Laryngoscope (2022)
**PMID:** 35699589 | **PMCID:** —
**DOI:** [10.1002/lary.30241](https://doi.org/10.1002/lary.30241)
**Fuente:** PubMed (abstract only)

## Relevancia
Tumores de cabeza y cuello (escamoso oro/hipo/laringe/sinonasal) tras quimioterapia de inducción: respuesta ganglionar cervical, manejo del cuello residual y desescalamiento de la radioterapia ganglionar electiva. Paralelismo con mama: la respuesta locorregional a inducción permite estratificar tratamientos posteriores y modificar el manejo quirúrgico/RT del cuello.

## Abstract
For hypopharyngeal carcinoma, metastatic neck nodes with a low response to induction chemotherapy (ICT) should not be managed with concomitant chemoradiotherapy. 153 hypopharyngeal carcinoma patients with regional metastasis treated with ICT were studied. Patients were divided into chemo-insensitive and chemosensitive groups. A nomogram based on five critical predictors (tumor differentiation, T classification, metastatic lymph node size, number of lymph node metastases, and cervical nodal necrosis) was developed. AUC values were 0.76 and 0.70. The nomogram yielded good accuracy in predicting the regional ICT response.

## Acceso
Vía [DOI](https://doi.org/10.1002/lary.30241) o suscripción institucional.

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*Datos de PubMed. Citar: doi 10.1002/lary.30241*
