# Highlights (Elsevier style)

Five bullets, maximum 85 characters each.

- 23 SRs (2006-2026) on axillary management after NAC synthesised in an umbrella review.
- TAD and RISAS deliver false-negative rate <5%; dual tracer and >=3 SLNs essential.
- Nodal pCR: 56-72% HR-/HER2+; 38-50% TNBC; 7-22% HR+/HER2-; >75% TNBC + IO.
- 7 guideline bodies converge: omit ALND in TAD-confirmed ypN0; omit RNI in cN1->ypN0.
- Gaps: ITC handling, chemo-IO era data, PROs and Latin-American validation pending.

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*Character counts (excluding leading "- " bullet marker): 80, 79, 76, 80, 79. All within the 85-character Elsevier limit. Bullet 1 updated 2026-05-14 (33 → 23) to match post-PICOS-triage corpus.*
